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Auteur Trenton W. J. Garner |
Documents disponibles écrits par cet auteur (6)
Affiner la rechercheAmphibian chytridiomycosis outbreak dynamics are linked with host skin bacterial community structure / Kieran A. Bates in Nature communications, 9 (1) (12/2018)
Titre : Amphibian chytridiomycosis outbreak dynamics are linked with host skin bacterial community structure Type de document : Imprimé Auteurs : Kieran A. Bates ; Frances C. Clare ; Simon O’Hanlon ; Jaime Bosch ; Lola Brookes ; Kevin Hopkins ; Emilia J. McLaughlin ; Olivia Daniel ; Trenton W. J. Garner ; Matthew C. Fisher ; Xavier A. Harrison Année de publication : 2018 Article en page(s) : 693 Langues : Français (fre) Catégories : [CBNPMP-Thématique] Enjeux de conservation des lacs d'altitude Lien pérenne : DOI : 10.1038/s41467-018-02967-w Permalink : https://biblio.cbnpmp.fr/index.php?lvl=notice_display&id=147849
in Nature communications > 9 (1) (12/2018) . - 693Bates, Kieran A., Clare, Frances C., O’Hanlon, Simon, Bosch, Jaime, Brookes, Lola, Hopkins, Kevin, McLaughlin, Emilia J., Daniel, Olivia, Garner, Trenton W. J., Fisher, Matthew C., Harrison, Xavier A. 2018 Amphibian chytridiomycosis outbreak dynamics are linked with host skin bacterial community structure. Nature communications, 9(1): 693.Documents numériques
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Article (2018)URL
Titre : Assessing the ability of swab data to determine the true burden of infection for the amphibian pathogen Batrachochytrium dendrobatidis Type de document : Imprimé Auteurs : Frances C. Clare ; Olivia Daniel ; Trenton W. J. Garner ; Matthew Fischer Année de publication : 2016 Article en page(s) : 360-367 Langues : Anglais (eng) Catégories : [CBNPMP-Thématique] Lac d'altitude Résumé : Batrachochytrium dendrobatidis (Bd) is a pathogenic fungus which causes the disease chytridiomycosis in amphibians by infecting the animals’ epidermis. The most commonly applied method for the detection of Bd is the use of a sterile swab, rubbed over the keratinized areas of an amphibian and then processed to yield DNA for detection by qPCR. This method has been used to infer a threshold of lethal infection in some species; however, how reliable and reproducible the swabbing method is at detecting the true burden of infection suffered by individuals is not known. European midwife toads, Alytes obstetricans, are susceptible to chytridiomycosis and are highly parasitised by Bd across Europe. By quantifying Bd-load throughout the entire skin and comparing this to swab results taken from the same individual, we determined whether epidermal swabs provide a quantifiable and accurate indication of the true fungal burden suffered. Further, we examined whether we could infer a threshold for lethal infection based on comparison of swab data taken from infected A. obstetricans exhibiting different clinical states. From swab data, we detected significantly higher fungal burdens from moribund metamorphs compared to visually healthy individuals; however, the ability of these swab data to provide an accurate indication of the true fungal burden was not reliable. These data suggest that fungal load dynamics play an important role in disease-induced mortality in A. obstetricans at these sites, but that using swab data to infer an exact threshold for Bd-associated mortality might be inappropriate and misleading. Lien pérenne : DOI : 10.1007/s10393-016-1114-z Permalink : https://biblio.cbnpmp.fr/index.php?lvl=notice_display&id=152363
in EcoHealth : conservation medicine, human health, ecosystem sustainability > 13 (2016) . - 360-367Clare, Frances C., Daniel, Olivia, Garner, Trenton W. J., Fischer, Matthew 2016 Assessing the ability of swab data to determine the true burden of infection for the amphibian pathogen Batrachochytrium dendrobatidis. EcoHealth : conservation medicine, human health, ecosystem sustainability, 13: 360-367.Documents numériques
Article (2016)URL
Titre : Climate forcing of an emerging pathogenic fungus across a montane multi-host community Type de document : Imprimé Auteurs : Frances C. Clare ; Julia B. Halder ; Olivia Daniel ; Jon Bielby ; Mikhail A. Semenov ; Thibaut Jombart ; Adeline Loyau ; Dirk S. Schmeller ; Andrew A. Cunningham ; Marcus Rowcliffe ; Trenton W. J. Garner ; Jaime Bosch ; Matthew C. Fisher Année de publication : 2016 Article en page(s) : 20150454 Langues : Anglais (eng) Catégories : [CBNPMP-Thématique] Enjeux de conservation des lacs d'altitude Résumé : Changes in the timings of seasonality as a result of anthropogenic climate change are predicted to occur over the coming decades. While this is expected to have widespread impacts on the dynamics of infectious disease through environmental forcing, empirical data are lacking. Here, we investigated whether seasonality, specifically the timing of spring ice-thaw, affected susceptibility to infection by the emerging pathogenic fungus Batrachochytrium dendrobatidis (Bd) across a montane community of amphibians that are suffering declines and extirpations as a consequence of this infection. We found a robust temporal association between the timing of the spring thaw and Bd infection in two host species, where we show that an early onset of spring forced high prevalences of infection. A third highly susceptible species (the midwife toad, Alytes obstetricans) maintained a high prevalence of infection independent of time of spring thaw. Our data show that perennially overwintering midwife toad larvae may act as a year-round reservoir of infection with variation in time of spring thaw determining the extent to which infection spills over into sympatric species. We used future temperature projections based on global climate models to demonstrate that the timing of spring thaw in this region will advance markedly by the 2050s, indicating that climate change will further force the severity of infection. Our findings on the effect of annual variability on multi-host infection dynamics show that the community-level impact of fungal infectious disease on biodiversity will need to be re-evaluated in the face of climate change. This article is part of the themed issue ‘Tackling emerging fungal threats to animal health, food security and ecosystem resilience’.
Lien pérenne : DOI : 10.1098/rstb.2015.0454 Permalink : https://biblio.cbnpmp.fr/index.php?lvl=notice_display&id=150964
in Philosophical Transactions Royal Society London B > 371 (2016) . - 20150454Clare, Frances C., Halder, Julia B., Daniel, Olivia, Bielby, Jon, Semenov, Mikhail A., Jombart, Thibaut, Loyau, Adeline, Schmeller, Dirk S., Cunningham, Andrew A., Rowcliffe, Marcus, Garner, Trenton W. J., Bosch, Jaime, Fisher, Matthew C. 2016 Climate forcing of an emerging pathogenic fungus across a montane multi-host community. Philosophical Transactions Royal Society London B, 371: 20150454.Documents numériques
Article (2016)URL
Titre : Collapse of Amphibian Communities Due to an Introduced Ranavirus Type de document : Imprimé Auteurs : Stephen J. Price ; Trenton W. J. Garner ; Richard A. Nichols ; François Balloux ; César Ayres ; Amparo Mora-Cabello de Alba ; Jaime Bosch Année de publication : 2014 Article en page(s) : 2586-2591 Langues : Anglais (eng) Catégories : [CBNPMP-Thématique] Lac d'altitude Résumé : The emergence of infectious diseases with a broad host range can have a dramatic impact on entire communities and has become one of the main threats to biodiversity [1-4]. Here, we report the simultaneous exploitation of entire communities of potential hosts with associated severe declines following invasion by a novel viral pathogen. We found two phylogenetically related, highly virulent viruses (genus Ranavirus, family Iridoviridae) causing mass mortality in multiple, diverse amphibian hosts in northern Spain, as well as a third, relatively avirulent virus. We document host declines in multiple species at multiple sites in the region. Our work reveals a group of pathogens that seem to have preexisting capacity to infect and evade immunity in multiple diverse and novel hosts, and that are exerting massive impacts on host communities. This report provides an exceptional record of host population trends being tracked in real time following emergence of a wildlife disease and a striking example of a novel, generalist pathogen repeatedly crossing the species barrier with catastrophic consequences at the level of host communities. Lien pérenne : DOI : 10.1016/j.cub.2014.09.028 Permalink : https://biblio.cbnpmp.fr/index.php?lvl=notice_display&id=152371
in Current biology > 24 (21) (2014) . - 2586-2591Price, Stephen J., Garner, Trenton W. J., Nichols, Richard A., Balloux, François, Ayres, César, Mora-Cabello de Alba, Amparo, Bosch, Jaime 2014 Collapse of Amphibian Communities Due to an Introduced Ranavirus. Current biology, 24(21): 2586-2591.Documents numériques
Article (2014)URL
Titre : From fish to frogs and beyond: Impact and host range of emergent ranaviruses Type de document : Imprimé Auteurs : Stephen J. Price ; Ellen Ariel ; Alicia Maclaine ; Gonçalo M. Rosa ; Maththew J. Gray ; Jesse L. Brunner ; Trenton W. J. Garner Année de publication : 2017 Article en page(s) : 272-279 Langues : Anglais (eng) Catégories : [CBNPMP-Thématique] Lac d'altitude
[CBNPMP-Thématique] Pollution de l'eauRésumé : Ranaviruses are pathogens of ectothermic vertebrates, including amphibians. We reviewed patterns of host range and virulence of ranaviruses in the context of virus genotype and postulate that patterns reflect significant variation in the historical and current host range of three groups of Ranavirus: FV3-like, CMTV-like and ATV-like ranaviruses. Our synthesis supports previous hypotheses about host range and jumps: FV3s are amphibian specialists, while ATVs are predominantly fish specialists that switched once to caudate amphibians. The most recent common ancestor of CMTV-like ranaviruses and FV3-like forms appears to have infected amphibians but CMTV-like ranaviruses may circulate in both amphibian and fish communities independently. While these hypotheses are speculative, we hope that ongoing efforts to describe ranavirus genetics, increased surveillance of host species and targeted experimental assays of susceptibility to infection and/or disease will facilitate better tests of the importance of hypothetical evolutionary drivers of ranavirus virulence and host range. Lien pérenne : DOI : 10.1016/j.virol.2017.08.001 Permalink : https://biblio.cbnpmp.fr/index.php?lvl=notice_display&id=152373
in Virology > 511 (2017) . - 272-279Price, Stephen J., Ariel, Ellen, Maclaine, Alicia, Rosa, Gonçalo M., Gray, Maththew J., Brunner, Jesse L., Garner, Trenton W. J. 2017 From fish to frogs and beyond: Impact and host range of emergent ranaviruses. Virology, 511: 272-279.Documents numériques
Article (2017)URL
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